Search details
1.
Fluorescent probes and degraders of the sterol transport protein Aster-A.
Bioorg Med Chem
; 103: 117673, 2024 Apr 01.
Article
in English
| MEDLINE | ID: mdl-38518734
2.
Identification of Biologically Diverse Tetrahydronaphthalen-2-ols through the Synthesis and Phenotypic Profiling of Chemically Diverse, Estradiol-Inspired Compounds.
Chembiochem
; 24(5): e202200555, 2023 03 01.
Article
in English
| MEDLINE | ID: mdl-36594441
3.
PSL Chemical Biology Symposia Third Edition: A Branch of Science in its Explosive Phase.
Chembiochem
; 24(8): e202300093, 2023 04 17.
Article
in English
| MEDLINE | ID: mdl-36942862
4.
Small molecule probes for targeting autophagy.
Nat Chem Biol
; 17(6): 653-664, 2021 06.
Article
in English
| MEDLINE | ID: mdl-34035513
5.
Structure, function and small molecule modulation of intracellular sterol transport proteins.
Bioorg Med Chem
; 68: 116856, 2022 08 15.
Article
in English
| MEDLINE | ID: mdl-35716590
6.
The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis.
Nat Chem Biol
; 15(7): 710-720, 2019 07.
Article
in English
| MEDLINE | ID: mdl-31222192
7.
Identification of Inhibitors of Cholesterol Transport Proteins Through the Synthesis of a Diverse, Sterol-Inspired Compound Collection.
Angew Chem Int Ed Engl
; 60(51): 26755-26761, 2021 12 13.
Article
in English
| MEDLINE | ID: mdl-34626154
8.
Pseudo Natural Products-Chemical Evolution of Natural Product Structure.
Angew Chem Int Ed Engl
; 60(29): 15705-15723, 2021 07 12.
Article
in English
| MEDLINE | ID: mdl-33644925
9.
Phenotyping Reveals Targets of a Pseudo-Natural-Product Autophagy Inhibitor.
Angew Chem Int Ed Engl
; 59(30): 12470-12476, 2020 07 20.
Article
in English
| MEDLINE | ID: mdl-32108411
10.
Image-Based Morphological Profiling Identifies a Lysosomotropic, Iron-Sequestering Autophagy Inhibitor.
Angew Chem Int Ed Engl
; 59(14): 5721-5729, 2020 03 27.
Article
in English
| MEDLINE | ID: mdl-31769920
11.
Modulation of autophagy by the novel mitochondrial complex I inhibitor Authipyrin.
Bioorg Med Chem
; 27(12): 2444-2448, 2019 06 15.
Article
in English
| MEDLINE | ID: mdl-30795990
12.
Synthesis of Indomorphan Pseudo-Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3.
Angew Chem Int Ed Engl
; 58(47): 17016-17025, 2019 11 18.
Article
in English
| MEDLINE | ID: mdl-31469221
13.
Natural product inspired compound collections: evolutionary principle, chemical synthesis, phenotypic screening, and target identification.
Drug Discov Today Technol
; 23: 75-82, 2017 Mar.
Article
in English
| MEDLINE | ID: mdl-28647090
14.
Discovery of Novel Cinchona-Alkaloid-Inspired Oxazatwistane Autophagy Inhibitors.
Angew Chem Int Ed Engl
; 56(8): 2145-2150, 2017 02 13.
Article
in English
| MEDLINE | ID: mdl-28097798
15.
Highly Enantioselective Catalytic Vinylogous Propargylation of Coumarins Yields a Class of Autophagy Inhibitors.
Angew Chem Int Ed Engl
; 56(37): 11232-11236, 2017 09 04.
Article
in English
| MEDLINE | ID: mdl-28696533
16.
Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34.
Angew Chem Int Ed Engl
; 56(28): 8153-8157, 2017 07 03.
Article
in English
| MEDLINE | ID: mdl-28544137
17.
Making bubbles: Targeting VPS41 induces vacuolization and methuosis.
Cell Chem Biol
; 30(2): 127-129, 2023 02 16.
Article
in English
| MEDLINE | ID: mdl-36800990
18.
Redshifted and thermally bistable one-way quantitative hemithioindigo-derived photoswitches enabled by isomer-specific excited state intramolecular proton transfer.
Chem Commun (Camb)
; 59(5): 563-566, 2023 Jan 12.
Article
in English
| MEDLINE | ID: mdl-36537010
19.
Identification of non-conventional small molecule degraders and stabilizers of squalene synthase.
Chem Sci
; 14(45): 12973-12983, 2023 Nov 22.
Article
in English
| MEDLINE | ID: mdl-38023519
20.
Identification of 5-HT2 Serotonin Receptor Modulators through the Synthesis of a Diverse, Tropane- and Quinuclidine-alkaloid-Inspired Compound Library.
J Med Chem
; 66(16): 11536-11554, 2023 08 24.
Article
in English
| MEDLINE | ID: mdl-37566000